人 ATG10 (NM_031482) cDNA克隆

Accession: NM_031482
基因名称: ATG10
基因别名: APG10; APG10L; pp12616
基因描述: Homo sapiens autophagy related 10 (ATG10), transcript variant 2, mRNA.
种属: Human
CDS区长度: 663 (查看编码区序列)
翻译后氨基酸长度: 220 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an exon in the 5' UTR, as compared to variant 1.
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G119235 人 ATG10 (NM_031482) cDNA克隆 pDONR223 2ug质粒 点击询价

Autophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12 (MIM 609608)-ATG5 (MIM 604261) conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A; MIM 601242), a homolog of yeast Apg8, to a membrane-bound form (Nemoto et al., 2003 [PubMed 12890687]).[supplied by OMIM, Mar 2008]