人 KRT4 (NM_002272) cDNA克隆

Accession: NM_002272
基因名称: KRT4
基因别名: K4; CK4; CK-4; CYK4
基因描述: Homo sapiens keratin 4 (KRT4), mRNA.
种属: Human
CDS区长度: 1563 (查看编码区序列)
翻译后氨基酸长度: 520 (查看氨基酸序列)
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G119284 人 KRT4 (NM_002272) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in differentiated layers of the mucosal and esophageal epithelia with family member KRT13. Mutations in these genes have been associated with White Sponge Nevus, characterized by oral, esophageal, and anal leukoplakia. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008]