人 CALCA (NM_001033952) cDNA克隆

基本信息

Accession: NM_001033952
基因名称: CALCA
基因别名: CT; KC; CGRP; CALC1; CGRP1; CGRP-I
基因描述: Homo sapiens calcitonin-related polypeptide alpha (CALCA), transcript variant 2, mRNA.
种属: Human
CDS区长度: 426 (查看编码区序列)
翻译后氨基酸长度: 141 (查看氨基酸序列)
Transcript Variant: This variant (2) has an alternate 3' coding region and 3' UTR compared to variant 3. The resulting protein has a longer and distinct C-terminus compared to calcitonin gene-related peptide 1. Variants 1 and 2 encode the same protein, which is cleaved to yield calcitonin (CT), a thyroid peptide-hormone product, and katacalcin peptides.

订购信息

产品编号 产品名称 载体 规格 价格
G119494 人 CALCA (NM_001033952) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 CALCA (NM_001741) cDNA克隆 transcript variant 1
人 CALCA (NM_001033952) cDNA克隆 transcript variant 2
人 CALCA (NM_001033953) cDNA克隆 transcript variant 3

基因简介

This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2009]

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