人 SP1 (NM_001251825) cDNA克隆

基本信息

Accession: NM_001251825
基因名称: SP1
基因描述: Homo sapiens Sp1 transcription factor (SP1), transcript variant 3, mRNA.
种属: Human
CDS区长度: 2214 (查看编码区序列)
翻译后氨基酸长度: 737 (查看氨基酸序列)
Transcript Variant: This variant (3) uses an alternate in-frame splice junction at the 5' end of an exon compared to variant 1. The resulting isoform (c) has the same N- and C-termini but is shorter compared to isoform a.

订购信息

产品编号 产品名称 载体 规格 价格
G119601 人 SP1 (NM_001251825) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 SP1 (NM_138473) cDNA克隆 transcript variant 1
人 SP1 (NM_003109) cDNA克隆 transcript variant 2
人 SP1 (NM_001251825) cDNA克隆 transcript variant 3

基因简介

The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

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