人 CALCR (NM_001164738) cDNA克隆

Accession: NM_001164738
基因名称: CALCR
基因别名: CRT; CTR; CT-R; CTR1
基因描述: Homo sapiens calcitonin receptor (CALCR), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1425 (查看编码区序列)
翻译后氨基酸长度: 474 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus, compared to isoform 1. Variants 2 and 3 encode the same isoform (2).
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G119626 人 CALCR (NM_001164738) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]