人 CD200R1 (NM_138940) cDNA克隆

Accession: NM_138940
基因名称: CD200R1
基因别名: OX2R; MOX2R; CD200R; HCRTR2
基因描述: Homo sapiens CD200 receptor 1 (CD200R1), transcript variant 3, mRNA.
种属: Human
CDS区长度: 498 (查看编码区序列)
翻译后氨基酸长度: 165 (查看氨基酸序列)
Transcript Variant: This variant (3) contains multiple differences in the coding region, compared to variant 1. This results in a frameshift and early stop codon, as well as loss of an immunoglobulin and transmembrane domain in the protein (isoform c), compared to isoform a.
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G119790 人 CD200R1 (NM_138940) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a receptor for the OX-2 membrane glycoprotein. Both the receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains. This receptor is restricted to the surfaces of myeloid lineage cells and the receptor-substrate interaction may function as a myeloid downregulatory signal. Mouse studies of a related gene suggest that this interaction may control myeloid function in a tissue-specific manner. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]