人 CROT (NM_001243745) cDNA克隆

Accession: NM_001243745
基因名称: CROT
基因别名: COT
基因描述: Homo sapiens carnitine O-octanoyltransferase (CROT), transcript variant 3, mRNA.
种属: Human
CDS区长度: 264 (查看编码区序列)
翻译后氨基酸长度: 87 (查看氨基酸序列)
Transcript Variant: This variant (3) includes an alternate segment and a distinct 3' UTR compared to variant 1. The encoded isoform (3) is significantly shorter and has a distinct C-terminus, compared to isoform 1.
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G119801 人 CROT (NM_001243745) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the carnitine/choline acetyltransferase family. The encoded protein converts 4,8-dimethylnonanoyl-CoA to its corresponding carnitine ester. This transesterification occurs in the peroxisome and is necessary for transport of medium- and long- chain acyl-CoA molecules out of the peroxisome to the cytosol and mitochondria. The protein thus plays a role in lipid metabolism and fatty acid beta-oxidation. Alternatively spliced transcript variants have been described.[provided by RefSeq, Jan 2009]