人 DLC1 (NM_006094) cDNA克隆

基本信息

Accession: NM_006094
基因名称: DLC1
基因别名: HP; ARHGAP7; STARD12; p122-RhoGAP
基因描述: Homo sapiens deleted in liver cancer 1 (DLC1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 3276 (查看编码区序列)
翻译后氨基酸长度: 1091 (查看氨基酸序列)
Transcript Variant: This variant (2) contains a distinct 5' UTR, lacks a portion of the 5' coding region, and represents use of an alternate promoter, compared to variant 1. The encoded isoform (2) has a distinct N-terminus and is shorter than isoform 1. Variant 2 represents the predominant transcript.

订购信息

产品编号 产品名称 载体 规格 价格
G119806 人 DLC1 (NM_006094) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 DLC1 (NM_182643) cDNA克隆 transcript variant 1
人 DLC1 (NM_006094) cDNA克隆 transcript variant 2
人 DLC1 (NM_024767) cDNA克隆 transcript variant 3
人 DLC1 (NM_001164271) cDNA克隆 transcript variant 4

基因简介

This gene encodes a GTPase-activating protein (GAP) that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene.[provided by RefSeq, Apr 2010]

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