人 ANKS1B (NM_152788) cDNA克隆

Accession: NM_152788
基因名称: ANKS1B
基因别名: EB1; AIDA; EB-1; ANKS2; AIDA-1; cajalin-2
基因描述: Homo sapiens ankyrin repeat and sterile alpha motif domain containing 1B (ANKS1B), transcript variant 1, mRNA.
种属: Human
CDS区长度: 3747 (查看编码区序列)
翻译后氨基酸长度: 1248 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a, also known as AIDA-1b).
产品编号 产品名称 载体 规格 价格
G120071 人 ANKS1B (NM_152788) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a multi-domain protein that is predominantly expressed in brain and testis. This protein interacts with amyloid beta protein precursor (AbetaPP) and may have a role in normal brain development, and in the pathogenesis of Alzheimer's disease. Expression of this gene has been shown to be elevated in patients with pre-B cell acute lymphocytic leukemia associated with t(1;19) translocation. Alternatively spliced transcript variants encoding different isoforms (some with different subcellular localization, PMID:15004329) have been described for this gene. [provided by RefSeq, Aug 2011]