人 CD6 (NM_001254750) cDNA克隆

Accession: NM_001254750
基因名称: CD6
基因别名: TP120
基因描述: Homo sapiens CD6 molecule (CD6), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1806 (查看编码区序列)
翻译后氨基酸长度: 601 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks two alternate in-frame exons in the 3' coding region compared to variant 1. The resulting protein (isoform 2) is shorter compared to isoform 1.
产品编号 产品名称 载体 规格 价格
G120774 人 CD6 (NM_001254750) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. This gene may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]