人 OSBPL5 (NM_145638) cDNA克隆

Accession: NM_145638
基因名称: OSBPL5
基因别名: ORP5; OBPH1
基因描述: Homo sapiens oxysterol binding protein-like 5 (OSBPL5), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2436 (查看编码区序列)
翻译后氨基酸长度: 811 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR and lacks an in-frame exon compared to variant 1, resulting in a shorter isoform (b) compared to isoform a. Isoform b has a sterol-binding domain but lacks a complete pleckstrin homology domain. Variants 2 and 3 encode the same protein.
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G120852 人 OSBPL5 (NM_145638) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors that play a key role in the maintenance of cholesterol balance in the body. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. This gene has been shown to be imprinted, with preferential expression from the maternal allele only in placenta. Transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2010]