The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin-1 participates in triggering neurotransmitter release at the synapse (Fernandez-Chacon et al., 2001 [PubMed 11242035]).[supplied by OMIM, Jul 2010]
人 SYT1 (NM_005639) cDNA克隆
| Accession: | NM_005639 |
|---|---|
| 基因名称: | SYT1 |
| 基因别名: | P65; SYT; SVP65 |
| 基因描述: | Homo sapiens synaptotagmin I (SYT1), transcript variant 1, mRNA. |
| 种属: | Human |
| CDS区长度: | 1269 (查看编码区序列) |
| 翻译后氨基酸长度: | 422 (查看氨基酸序列) |
| Transcript Variant: | This variant (1) represents the more commonly exptressed transcript. Variants 1, 2, and 3 encode the same protein. |
| 人 SYT1 (NM_005639) cDNA克隆 | transcript variant 1 |
| 人 SYT1 (NM_001135805) cDNA克隆 | transcript variant 2 |
| 人 SYT1 (NM_001135806) cDNA克隆 | transcript variant 3 |
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