人 ELMO1 (NM_130442) cDNA克隆

基本信息

Accession: NM_130442
基因名称: ELMO1
基因别名: CED12; CED-12; ELMO-1
基因描述: Homo sapiens engulfment and cell motility 1 (ELMO1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 744 (查看编码区序列)
翻译后氨基酸长度: 247 (查看氨基酸序列)
Transcript Variant: This variant (2) represents use of an alternate promoter and differs in the 5' UTR and 5' coding region, compared to variant 1. These differences cause translation initiation at a downstream AUG and result in an isoform (2) with a shorter N-terminus, compared to isoform 1. Both variants 2 and 3 encode the same isoform (2).

订购信息

产品编号 产品名称 载体 规格 价格
G121094 人 ELMO1 (NM_130442) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 ELMO1 (NM_014800) cDNA克隆 transcript variant 1
人 ELMO1 (NM_130442) cDNA克隆 transcript variant 2
人 ELMO1 (NM_001039459) cDNA克隆 transcript variant 3
人 ELMO1 (NM_001206480) cDNA克隆 transcript variant 4
人 ELMO1 (NM_001206482) cDNA克隆 transcript variant 5

基因简介

This gene encodes a member of the engulfment and cell motility protein family. These proteins interact with dedicator of cytokinesis proteins to promote phagocytosis and cell migration. Increased expression of this gene and dedicator of cytokinesis 1 may promote glioma cell invasion, and single nucleotide polymorphisms in this gene may be associated with diabetic nephropathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

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