人 ABCE1 (NM_001040876) cDNA克隆

Accession: NM_001040876
基因名称: ABCE1
基因别名: RLI; OABP; ABC38; RNS4I; RNASEL1; RNASELI
基因描述: Homo sapiens ATP-binding cassette, sub-family E (OABP), member 1 (ABCE1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1800 (查看编码区序列)
翻译后氨基酸长度: 599 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein.
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G121164 人 ABCE1 (NM_001040876) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]