人 BRMS1 (NM_015399) cDNA克隆

Accession: NM_015399
基因名称: BRMS1
基因描述: Homo sapiens breast cancer metastasis suppressor 1 (BRMS1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 741 (查看编码区序列)
翻译后氨基酸长度: 246 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest and more abundant transcript and encodes isoform (1).
产品编号 产品名称 载体 规格 价格
G121487 人 BRMS1 (NM_015399) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]