人 MDH1 (NM_005917) cDNA克隆

Accession: NM_005917
基因名称: MDH1
基因别名: MDHA; MOR2; MDH-s; MGC:1375
基因描述: Homo sapiens malate dehydrogenase 1, NAD (soluble) (MDH1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1005 (查看编码区序列)
翻译后氨基酸长度: 334 (查看氨基酸序列)
Transcript Variant: This variant (2) has an alternate 5' exon compared to variant 1. The resulting isoform (2) is shorter at the N-terminus, as compared to isoform 1.
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G121567 人 MDH1 (NM_005917) cDNA克隆 pDONR223 2ug质粒 点击询价

Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the cytoplasm and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[provided by RefSeq, Nov 2010]