人 NGLY1 (NM_001145293) cDNA克隆

基本信息

Accession: NM_001145293
基因名称: NGLY1
基因别名: PNG1; CDG1V; PNGase
基因描述: Homo sapiens N-glycanase 1 (NGLY1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1911 (查看编码区序列)
翻译后氨基酸长度: 636 (查看氨基酸序列)
Transcript Variant: This variant (2) includes an alternate exon that causes a frameshift and lacks an alternate exon which restores the reading frame, compared to variant 1. The resulting protein (isoform 2) is shorter compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G121585 人 NGLY1 (NM_001145293) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 NGLY1 (NM_018297) cDNA克隆 transcript variant 1
人 NGLY1 (NM_001145293) cDNA克隆 transcript variant 2
人 NGLY1 (NM_001145294) cDNA克隆 transcript variant 3
人 NGLY1 (NM_001145295) cDNA克隆 transcript variant 4

基因简介

This gene encodes an enzyme that catalyzes hydrolysis of an N(4)-(acetyl-beta-D-glucosaminyl) asparagine residue to N-acetyl-beta-D-glucosaminylamine and a peptide containing an aspartate residue. The encoded enzyme may play a role in the proteasome-mediated degradation of misfolded glycoproteins. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2009]

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