人 CTAG2 (NM_172377) cDNA克隆

Accession: NM_172377
基因名称: CTAG2
基因别名: CT2; ESO2; CAMEL; CT6.2; CT6.2a; CT6.2b; LAGE-1; LAGE2B
基因描述: Homo sapiens cancer/testis antigen 2 (CTAG2), transcript variant 1, mRNA.
种属: Human
CDS区长度: 543 (查看编码区序列)
翻译后氨基酸长度: 180 (查看氨基酸序列)
Transcript Variant: This variant (1) encodes isoform LAGE-1a (also known as LAGE-1S).
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G121810 人 CTAG2 (NM_172377) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes an autoimmunogenic tumor antigen that belongs to the ESO/LAGE family of cancer-testis antigens. This protein is expressed in a wide array of cancers including melanoma, breast cancer, bladder cancer and prostate cancer. This protein is also expressed in normal testis tissue. An alternative open reading frame product of this gene has been described in PMID:10399963. This alternate protein, termed CAMEL, is a tumor antigen that is recognized by melanoma-specific cytotoxic T-lymphocytes. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]