人 AES (NM_198970) cDNA克隆

Accession: NM_198970
基因名称: AES
基因别名: GRG; ESP1; GRG5; TLE5; AES-1; AES-2
基因描述: Homo sapiens amino-terminal enhancer of split (AES), transcript variant 3, mRNA.
种属: Human
CDS区长度: 591 (查看编码区序列)
翻译后氨基酸长度: 196 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 5' UTR and coding region compared to variant 1. The resulting isoform (c) is shorter, has a distinct N-terminus, and lacks 1 aa in the C-terminus compared to isoform a.
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G121908 人 AES (NM_198970) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]