人 OPCML (NM_001012393) cDNA克隆

Accession: NM_001012393
基因名称: OPCML
基因别名: OPCM; OBCAM; IGLON1
基因描述: Homo sapiens opioid binding protein/cell adhesion molecule-like (OPCML), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1017 (查看编码区序列)
翻译后氨基酸长度: 338 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR and coding region compared to variant 1. The resulting isoform (b) is shorter and has a distinct N-terminus compared to isoform a.
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G122011 人 OPCML (NM_001012393) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the IgLON subfamily in the immunoglobulin protein superfamily. The encoded protein is localized in the plasma membrane and may have an accessory role in opioid receptor function. This gene has an ortholog in rat and bovine. The opioid binding-cell adhesion molecule encoded by the rat gene binds opioid alkaloids in the presence of acidic lipids, exhibits selectivity for mu ligands and acts as a GPI-anchored protein. Since the encoded protein is highly conserved in species during evolution, it may have a fundamental role in mammalian systems. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]