人 CBLL1 (NM_001284291) cDNA克隆

Accession: NM_001284291
基因名称: CBLL1
基因别名: HAKAI; RNF188
基因描述: Homo sapiens Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase (CBLL1), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1473 (查看编码区序列)
翻译后氨基酸长度: 490 (查看氨基酸序列)
Transcript Variant: This variant (3) uses an alternate in-frame splice site in the 5' coding region. The encoded isoform (2) is shorter than isoform (1).
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G122089 人 CBLL1 (NM_001284291) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes an E3 ubiquitin-ligase for the E-cadherin complex and mediates its ubiquitination, endocytosis, and degradation in the lysosomes. The encoded protein contains a RING-finger domain and is also thought to have a role in control of cell proliferation. A related pseudogene has been identified on chromosome X. Alternative splicing results in a non-coding transcript variant. [provided by RefSeq, Aug 2011]