人 HFE (NM_139011) cDNA克隆

基本信息

Accession: NM_139011
基因名称: HFE
基因别名: HH; HFE1; HLA-H; MVCD7; TFQTL2
基因描述: Homo sapiens hemochromatosis (HFE), transcript variant 11, mRNA.
种属: Human
CDS区长度: 231 (查看编码区序列)
翻译后氨基酸长度: 76 (查看氨基酸序列)
Transcript Variant: This variant (11) lacks a large internal part of the coding region but the reading frame is maintained, as compared to variant 1. The protein encoded is the shortest isoform (11).

订购信息

产品编号 产品名称 载体 规格 价格
G122122 人 HFE (NM_139011) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 HFE (NM_000410) cDNA克隆 transcript variant 1
人 HFE (NM_139010) cDNA克隆 transcript variant 10
人 HFE (NM_139011) cDNA克隆 transcript variant 11
人 HFE (NM_139003) cDNA克隆 transcript variant 3
人 HFE (NM_139004) cDNA克隆 transcript variant 4
人 HFE (NM_139006) cDNA克隆 transcript variant 6
人 HFE (NM_139007) cDNA克隆 transcript variant 7
人 HFE (NM_139008) cDNA克隆 transcript variant 8
人 HFE (NM_139009) cDNA克隆 transcript variant 9

基因简介

The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]

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