人 LIPF (NM_001198828) cDNA克隆

Accession: NM_001198828
基因名称: LIPF
基因别名: GL; HGL; HLAL
基因描述: Homo sapiens lipase, gastric (LIPF), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1098 (查看编码区序列)
翻译后氨基酸长度: 365 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 5' UTR and coding sequence and uses an alternate in-frame splice junction at the 5' end of an exon compared to variant 1. The resulting isoform (3) is shorter at the N-terminus and lacks an internal segment compared to isoform 1.
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G122139 人 LIPF (NM_001198828) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes gastric lipase, an enzyme involved in the digestion of dietary triglycerides in the gastrointestinal tract, and responsible for 30% of fat digestion processes occurring in human. It is secreted by gastric chief cells in the fundic mucosa of the stomach, and it hydrolyzes the ester bonds of triglycerides under acidic pH conditions. The gene is a member of a conserved gene family of lipases that play distinct roles in neutral lipid metabolism. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]