人 ANGPT2 (NM_001118887) cDNA克隆

Accession: NM_001118887
基因名称: ANGPT2
基因别名: ANG2; AGPT2
基因描述: Homo sapiens angiopoietin 2 (ANGPT2), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1488 (查看编码区序列)
翻译后氨基酸长度: 495 (查看氨基酸序列)
Transcript Variant: This variant (2) uses an alternate in-frame splice site compared to variant 1, resulting in an isoform (b) that lacks an internal aa compared to isoform a.
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G122240 人 ANGPT2 (NM_001118887) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE-2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]