人 KCNQ5 (NM_001160132) cDNA克隆

基本信息

Accession: NM_001160132
基因名称: KCNQ5
基因别名: Kv7.5
基因描述: Homo sapiens potassium voltage-gated channel, KQT-like subfamily, member 5 (KCNQ5), transcript variant 3, mRNA.
种属: Human
CDS区长度: 2829 (查看编码区序列)
翻译后氨基酸长度: 942 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks an alternate in-frame exon in the central coding region, compared to variant 4. The resulting isoform (3), also known as III, lacks an internal segment compared to isoform 4.

订购信息

产品编号 产品名称 载体 规格 价格
G122287 人 KCNQ5 (NM_001160132) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 KCNQ5 (NM_019842) cDNA克隆 transcript variant 1
人 KCNQ5 (NM_001160130) cDNA克隆 transcript variant 2
人 KCNQ5 (NM_001160132) cDNA克隆 transcript variant 3
人 KCNQ5 (NM_001160133) cDNA克隆 transcript variant 4
人 KCNQ5 (NM_001160134) cDNA克隆 transcript variant 5

基因简介

This gene is a member of the KCNQ potassium channel gene family that is differentially expressed in subregions of the brain and in skeletal muscle. The protein encoded by this gene yields currents that activate slowly with depolarization and can form heteromeric channels with the protein encoded by the KCNQ3 gene. Currents expressed from this protein have voltage dependences and inhibitor sensitivities in common with M-currents. They are also inhibited by M1 muscarinic receptor activation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]

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