人 CNKSR2 (NM_001168648) cDNA克隆

Accession: NM_001168648
基因名称: CNKSR2
基因别名: CNK2; KSR2; MAGUIN
基因描述: Homo sapiens connector enhancer of kinase suppressor of Ras 2 (CNKSR2), transcript variant 3, mRNA.
种属: Human
CDS区长度: 2697 (查看编码区序列)
翻译后氨基酸长度: 898 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 3' UTR and 3' coding region, compared to variant 1. It encodes isoform 3 which has a shorter and distinct C-terminus, compared to isoform 1. Variant 3 is also known as CNK2B and MAGUIN-2.
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G122424 人 CNKSR2 (NM_001168648) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a multidomain protein that functions as a scaffold protein to mediate the mitogen-activated protein kinase pathways downstream from Ras. This gene product is induced by vitamin D and inhibits apoptosis in certain cancer cells. It may also play a role in ternary complex assembly of synaptic proteins at the postsynaptic membrane and coupling of signal transduction to membrane/cytoskeletal remodeling. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]