人 ITSN1 (NM_003024) cDNA克隆

Accession: NM_003024
基因名称: ITSN1
基因别名: ITSN; SH3D1A; SH3P17
基因描述: Homo sapiens intersectin 1 (SH3 domain protein) (ITSN1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 5166 (查看编码区序列)
翻译后氨基酸长度: 1721 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (ITSN-l).
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G122467 人 ITSN1 (NM_003024) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a cytoplasmic membrane-associated protein that indirectly coordinates endocytic membrane traffic with the actin assembly machinery. In addition, the encoded protein may regulate the formation of clathrin-coated vesicles and could be involved in synaptic vesicle recycling. This protein has been shown to interact with dynamin, CDC42, SNAP23, SNAP25, SPIN90, EPS15, EPN1, EPN2, and STN2. Multiple transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them have been characterized so far. [provided by RefSeq, Jul 2008]