人 GRIA1 (NM_001114183) cDNA克隆

Accession: NM_001114183
基因名称: GRIA1
基因别名: GLUH1; GLUR1; GLURA; GluA1; HBGR1
基因描述: Homo sapiens glutamate receptor, ionotropic, AMPA 1 (GRIA1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2721 (查看编码区序列)
翻译后氨基酸长度: 906 (查看氨基酸序列)
Transcript Variant: This variant (2) has a different coding exon in the 3' region, as compared to variant 1. The resulting isoform (2) is the same length but has a different internal segment, as compared to isoform 1.
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G122600 人 GRIA1 (NM_001114183) cDNA克隆 pDONR223 2ug质粒 点击询价

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]