人 TGFBR3 (NM_003243) cDNA克隆

Accession: NM_003243
基因名称: TGFBR3
基因别名: BGCAN; betaglycan
基因描述: Homo sapiens transforming growth factor, beta receptor III (TGFBR3), transcript variant 1, mRNA.
种属: Human
CDS区长度: 2556 (查看编码区序列)
翻译后氨基酸长度: 851 (查看氨基酸序列)
Transcript Variant: This variant (1) encodes the longer isoform (a).
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G122693 人 TGFBR3 (NM_003243) cDNA克隆 pDONR223 2ug质粒 点击询价

This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.[provided by RefSeq, Sep 2010]