人 TRPC4 (NM_001135955) cDNA克隆

基本信息

Accession: NM_001135955
基因名称: TRPC4
基因别名: TRP4; HTRP4; HTRP-4
基因描述: Homo sapiens transient receptor potential cation channel, subfamily C, member 4 (TRPC4), transcript variant beta, mRNA.
种属: Human
CDS区长度: 2682 (查看编码区序列)
翻译后氨基酸长度: 893 (查看氨基酸序列)
Transcript Variant: This variant (beta) lacks an in-frame segment in the 3' coding region, compared to variant alpha. The resulting protein (isoform beta) is shorter when it is compared to isoform alpha.

订购信息

产品编号 产品名称 载体 规格 价格
G122706 人 TRPC4 (NM_001135955) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 TRPC4 (NM_016179) cDNA克隆 transcript variant alpha
人 TRPC4 (NM_001135955) cDNA克隆 transcript variant beta
人 TRPC4 (NM_001135957) cDNA克隆 transcript variant delta
人 TRPC4 (NM_003306) cDNA克隆 transcript variant epsilon
人 TRPC4 (NM_001135956) cDNA克隆 transcript variant gamma
人 TRPC4 (NM_001135958) cDNA克隆 transcript variant zeta

基因简介

This gene encodes a member of the canonical subfamily of transient receptor potential cation channels. The encoded protein forms a non-selective calcium-permeable cation channel that is activated by Gq-coupled receptors and tyrosine kinases, and plays a role in multiple processes including endothelial permeability, vasodilation, neurotransmitter release and cell proliferation. Single nucleotide polymorphisms in this gene may be associated with generalized epilepsy with photosensitivity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]

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