人 CLCN4 (NM_001256944) cDNA克隆

基本信息

Accession: NM_001256944
基因名称: CLCN4
基因别名: CLC4; ClC-4; ClC-4A
基因描述: Homo sapiens chloride channel, voltage-sensitive 4 (CLCN4), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2001 (查看编码区序列)
翻译后氨基酸长度: 666 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR and lacks an in-frame portion of the 5' coding region, compared to variant 1. The resulting isoform (2) has a shorter N-terminus, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G122775 人 CLCN4 (NM_001256944) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 CLCN4 (NM_001830) cDNA克隆 transcript variant 1
人 CLCN4 (NM_001256944) cDNA克隆 transcript variant 2

基因简介

The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. Chloride channel 4 has an evolutionary conserved CpG island and is conserved in both mouse and hamster. This gene is mapped in close proximity to APXL (Apical protein Xenopus laevis-like) and OA1 (Ocular albinism type I), which are both located on the human X chromosome at band p22.3. The physiological role of chloride channel 4 remains unknown but may contribute to the pathogenesis of neuronal disorders. Alternate splicing results in two transcript variants that encode different proteins. [provided by RefSeq, Mar 2012]

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