人 AMOT (NM_133265) cDNA克隆

基本信息

Accession: NM_133265
基因名称: AMOT
基因描述: Homo sapiens angiomotin (AMOT), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2028 (查看编码区序列)
翻译后氨基酸长度: 675 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. This difference results in translation initiation at a downstream ATG and an isoform (2) with a shorter N-terminus, compared to isoform 1. This isoform lacks the N-terminal extension present in isoform 1 that mediates association with cytoplasmic F-actin.

订购信息

产品编号 产品名称 载体 规格 价格
G122937 人 AMOT (NM_133265) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 AMOT (NM_001113490) cDNA克隆 transcript variant 1
人 AMOT (NM_133265) cDNA克隆 transcript variant 2

基因简介

This gene belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

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