人 ASAH2 (NM_019893) cDNA克隆

基本信息

Accession: NM_019893
基因名称: ASAH2
基因别名: HNAC1; BCDase; LCDase; NCDase; N-CDase
基因描述: Homo sapiens N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2 (ASAH2), transcript variant 1, mRNA.
种属: Human
CDS区长度: 2343 (查看编码区序列)
翻译后氨基酸长度: 780 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).

订购信息

产品编号 产品名称 载体 规格 价格
G122939 人 ASAH2 (NM_019893) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 ASAH2 (NM_019893) cDNA克隆 transcript variant 1
人 ASAH2 (NM_001143974) cDNA克隆 transcript variant 2

基因简介

Ceramidases (EC 3.5.1.23), such as ASAH2, catalyze hydrolysis of the N-acyl linkage of ceramide, a second messenger in a variety of cellular events, to produce sphingosine. Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger (see MIM 603730) (Mitsutake et al., 2001 [PubMed 11328816]).[supplied by OMIM, Mar 2008]

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