人 TET2 (NM_017628) cDNA克隆

Accession: NM_017628
基因名称: TET2
基因别名: MDS; KIAA1546
基因描述: Homo sapiens tet methylcytosine dioxygenase 2 (TET2), transcript variant 2, mRNA.
种属: Human
CDS区长度: 3498 (查看编码区序列)
翻译后氨基酸长度: 1165 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR and in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (b) is shorter and has a distinct C-terminus compared to isoform a.
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G123081 人 TET2 (NM_017628) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defects in this gene have been associated with several myeloproliferative disorders. Two variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]