人 GRK4 (NM_001004057) cDNA克隆

Accession: NM_001004057
基因名称: GRK4
基因别名: IT11; GPRK4; GRK4a; GPRK2L
基因描述: Homo sapiens G protein-coupled receptor kinase 4 (GRK4), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1599 (查看编码区序列)
翻译后氨基酸长度: 532 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (gamma) has the same N- and C-termini but is shorter compared to isoform alpha.
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G123160 人 GRK4 (NM_001004057) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating its deactivation. This gene has been linked to both genetic and acquired hypertension. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]