人 IKBKE (NM_001193322) cDNA克隆

基本信息

Accession: NM_001193322
基因名称: IKBKE
基因别名: IKKE; IKKI; IKK-E; IKK-i
基因描述: Homo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon (IKBKE), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1974 (查看编码区序列)
翻译后氨基酸长度: 657 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an alternate segment in the 3' coding region, which shifts the reading frame, compared to variant 1. The resulting protein (isoform 2) has a shorter and distinct C-terminus when it is compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G123173 人 IKBKE (NM_001193322) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 IKBKE (NM_014002) cDNA克隆 transcript variant 1
人 IKBKE (NM_001193322) cDNA克隆 transcript variant 2
人 IKBKE (NM_001193321) cDNA克隆 transcript variant 3

基因简介

IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al., 2009 [PubMed 19481526]).[supplied by OMIM, Oct 2009]

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