人 SIM2 (NM_009586) cDNA克隆

Accession: NM_009586
基因名称: SIM2
基因别名: SIM; bHLHe15; HMC13F06; HMC29C01
基因描述: Homo sapiens single-minded family bHLH transcription factor 2 (SIM2), transcript variant SIM2s, mRNA.
种属: Human
CDS区长度: 1713 (查看编码区序列)
翻译后氨基酸长度: 570 (查看氨基酸序列)
Transcript Variant: The SIM2s protein includes an altered C-terminus encoded by part of intron 10.
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G123221 人 SIM2 (NM_009586) cDNA克隆 pDONR223 2ug质粒 点击询价
人 SIM2 (NM_005069) cDNA克隆 transcript variant SIM2
人 SIM2 (NM_009586) cDNA克隆 transcript variant SIM2s

SIM1 and SIM2 genes are Drosophila single-minded (sim) gene homologs. The Drosophila sim gene encodes a transcription factor that is a master regulator of fruit fly neurogenesis. SIM2 maps within the so-called Down syndrome chromosomal region. Based on the mapping position, its potential function as transcriptional repressor and similarity to Drosophila sim, it is proposed that SIM2 may contribute to some specific Down syndrome phenotypes [provided by RefSeq, Jul 2008]