人 KAT5 (NM_006388) cDNA克隆

Accession: NM_006388
基因名称: KAT5
基因别名: TIP; ESA1; PLIP; TIP60; cPLA2; HTATIP; ZC2HC5; HTATIP1
基因描述: Homo sapiens K(lysine) acetyltransferase 5 (KAT5), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1542 (查看编码区序列)
翻译后氨基酸长度: 513 (查看氨基酸序列)
Transcript Variant: This variant (2), also known as alpha, lacks an alternate in-frame segment, compared to variant 1, resulting in a shorter protein (isoform 2), that has a shorter N-terminus, compared to isoform 1.
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G123338 人 KAT5 (NM_006388) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]