人 ALDH8A1 (NM_022568) cDNA克隆

基本信息

Accession: NM_022568
基因名称: ALDH8A1
基因别名: ALDH12; DJ352A20.2
基因描述: Homo sapiens aldehyde dehydrogenase 8 family, member A1 (ALDH8A1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1464 (查看编码区序列)
翻译后氨基酸长度: 487 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longer transcript, and encodes the longer protein (isoform 1).

订购信息

产品编号 产品名称 载体 规格 价格
G123432 人 ALDH8A1 (NM_022568) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 ALDH8A1 (NM_022568) cDNA克隆 transcript variant 1
人 ALDH8A1 (NM_170771) cDNA克隆 transcript variant 2
人 ALDH8A1 (NM_001193480) cDNA克隆 transcript variant 3

基因简介

This protein belongs to the aldehyde dehydrogenases family of proteins. It plays a role in a pathway of 9-cis-retinoic acid biosynthesis in vivo. This enzyme converts 9-cis-retinal into the retinoid X receptor ligand 9-cis-retinoic acid, and has approximately 40-fold higher activity with 9-cis-retinal than with all-trans-retinal. Therefore, it is the first known aldehyde dehydrogenase to show a preference for 9-cis-retinal relative to all-trans-retinal. Three transcript variants encoding distinct protein isoforms have been identified for this gene. [provided by RefSeq, Jul 2010]

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