人 DAZ3 (NM_020364) cDNA克隆

Accession: NM_020364
基因名称: DAZ3
基因别名: pDP1679
基因描述: Homo sapiens deleted in azoospermia 3 (DAZ3), mRNA.
种属: Human
CDS区长度: 1317 (查看编码区序列)
翻译后氨基酸长度: 438 (查看氨基酸序列)
产品编号 产品名称 载体 规格 价格
G123490 人 DAZ3 (NM_020364) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications; one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat; the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified; this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains one copy of the 10.8 kb repeat. [provided by RefSeq, Jul 2008]