人 FBXW12 (NM_001159929) cDNA克隆

基本信息

Accession: NM_001159929
基因名称: FBXW12
基因别名: FBW12; FBXO12; FBXO35
基因描述: Homo sapiens F-box and WD repeat domain containing 12 (FBXW12), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1338 (查看编码区序列)
翻译后氨基酸长度: 445 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (3) has a distinct N-terminus and is shorter than isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G123498 人 FBXW12 (NM_001159929) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 FBXW12 (NM_207102) cDNA克隆 transcript variant 1
人 FBXW12 (NM_001159927) cDNA克隆 transcript variant 2
人 FBXW12 (NM_001159929) cDNA克隆 transcript variant 3

基因简介

Members of the F-box protein family, such as FBXW12, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603034), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]

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