人 RAET1E (NM_139165) cDNA克隆

Accession: NM_139165
基因名称: RAET1E
基因别名: RL-4; LETAL; ULBP4; N2DL-4; NKG2DL4; RAET1E2; bA350J20.7
基因描述: Homo sapiens retinoic acid early transcript 1E (RAET1E), transcript variant 1, mRNA.
种属: Human
CDS区长度: 792 (查看编码区序列)
翻译后氨基酸长度: 263 (查看氨基酸序列)
Transcript Variant: This variant (1) encodes the longest isoform (1).
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G123762 人 RAET1E (NM_139165) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene belong to the RAET1 family, which consists of major histocompatibility complex (MHC) class I-related genes located in a cluster on chromosome 6q24.2-q25.3. This and RAET1G protein differ from other RAET1 proteins in that they have type I membrane-spanning sequences at their C termini rather than glycosylphosphatidylinositol anchor sequences. This protein functions as a ligand for NKG2D receptor, which is expressed on the surface of several types of immune cells, and is involved in innate and adaptive immune responses. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2011]