人 P2RX6 (NM_001159554) cDNA克隆

Accession: NM_001159554
基因名称: P2RX6
基因别名: P2X6; P2XM; P2RXL1
基因描述: Homo sapiens purinergic receptor P2X, ligand-gated ion channel, 6 (P2RX6), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1248 (查看编码区序列)
翻译后氨基酸长度: 415 (查看氨基酸序列)
Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1, resulting in an isoform (2) that is shorter than isoform 1.
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G124314 人 P2RX6 (NM_001159554) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene belongs to the family of P2X receptors, which are ATP-gated ion channels and mediate rapid and selective permeability to cations. This gene is predominantly expressed in skeletal muscle, and regulated by p53. The encoded protein is associated with VE-cadherin at the adherens junctions of human umbilical vein endothelial cells. Alternative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 22, has been identified. [provided by RefSeq, Apr 2009]