人 PRICKLE1 (NM_001144882) cDNA克隆

基本信息

Accession: NM_001144882
基因名称: PRICKLE1
基因别名: RILP; EPM1B
基因描述: Homo sapiens prickle homolog 1 (Drosophila) (PRICKLE1), transcript variant 3, mRNA.
种属: Human
CDS区长度: 2496 (查看编码区序列)
翻译后氨基酸长度: 831 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1-4 encode the same protein.

订购信息

产品编号 产品名称 载体 规格 价格
G124438 人 PRICKLE1 (NM_001144882) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PRICKLE1 (NM_153026) cDNA克隆 transcript variant 1
人 PRICKLE1 (NM_001144881) cDNA克隆 transcript variant 2
人 PRICKLE1 (NM_001144882) cDNA克隆 transcript variant 3
人 PRICKLE1 (NM_001144883) cDNA克隆 transcript variant 4

基因简介

This gene encodes a nuclear receptor that may be a negative regulator of the Wnt/beta-catenin signaling pathway. The encoded protein localizes to the nuclear membrane and has been implicated in the nuclear trafficking of the transcription repressors REST/NRSF and REST4. Mutations in this gene have been linked to progressive myoclonus epilepsy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 3. [provided by RefSeq, Sep 2009]

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