人 VNN1 (NM_004666) cDNA克隆

Accession: NM_004666
基因名称: VNN1
基因别名: HDLCQ8; Tiff66
基因描述: Homo sapiens vanin 1 (VNN1), mRNA.
种属: Human
CDS区长度: 1542 (查看编码区序列)
翻译后氨基酸长度: 513 (查看氨基酸序列)
产品编号 产品名称 载体 规格 价格
G124474 人 VNN1 (NM_004666) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the vanin family of proteins, which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. This protein, like its mouse homolog, is likely a GPI-anchored cell surface molecule. The mouse protein is expressed by the perivascular thymic stromal cells and regulates migration of T-cell progenitors to the thymus. This gene lies in close proximity to, and in the same transcriptional orientation as, two other vanin genes on chromosome 6q23-q24. [provided by RefSeq, Feb 2009]