人 RAPGEF2 (NM_014247) cDNA克隆

基本信息

Accession: NM_014247
基因名称: RAPGEF2
基因别名: RA-GEF; NRAPGEP; PDZGEF1; Rap-GEP; CNrasGEF; PDZ-GEF1; RA-GEF-1; nRap GEP
基因描述: Homo sapiens Rap guanine nucleotide exchange factor (GEF) 2 (RAPGEF2), mRNA.
种属: Human
CDS区长度: 4500 (查看编码区序列)
翻译后氨基酸长度: 1499 (查看氨基酸序列)

订购信息

产品编号 产品名称 载体 规格 价格
G124738 人 RAPGEF2 (NM_014247) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

基因简介

Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF2, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM, Mar 2008]

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