人 RAPGEF1 (NM_005312) cDNA克隆

基本信息

Accession: NM_005312
基因名称: RAPGEF1
基因别名: C3G; GRF2
基因描述: Homo sapiens Rap guanine nucleotide exchange factor (GEF) 1 (RAPGEF1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 3234 (查看编码区序列)
翻译后氨基酸长度: 1077 (查看氨基酸序列)
Transcript Variant: This variant (1) differs in the 5' UTR compared to variant 2. This results in a shorter isoform (a) with a distinct N-terminus, compared to isoform b.

订购信息

产品编号 产品名称 载体 规格 价格
G145979 人 RAPGEF1 (NM_005312) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 RAPGEF1 (NM_005312) cDNA克隆 transcript variant 1
人 RAPGEF1 (NM_198679) cDNA克隆 transcript variant 2

基因简介

This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]

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