人 GPRASP1 (NM_001099410) cDNA克隆

Accession: NM_001099410
基因名称: GPRASP1
基因别名: GASP; GASP1; GASP-1
基因描述: Homo sapiens G protein-coupled receptor associated sorting protein 1 (GPRASP1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 4188 (查看编码区序列)
翻译后氨基酸长度: 1395 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an exon in the 5' UTR and encodes the same protein, as compared to variant 1.
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G124820 人 GPRASP1 (NM_001099410) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the GPRASP (G protein-coupled receptor associated sorting protein) family. The protein may modulate lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors. It targets receptors for degradation in lysosomes. The receptors interacting with this sorting protein include D2 dopamine receptor (DRD2), delta opioid receptor (OPRD1), beta-2 adrenergic receptor (ADRB2), D4 dopamine receptor (DRD4) and cannabinoid 1 receptor (CB1R). Multiple alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, May 2010]