人 SENP7 (NM_001282804) cDNA克隆

基本信息

Accession: NM_001282804
基因名称: SENP7
基因描述: Homo sapiens SUMO1/sentrin specific peptidase 7 (SENP7), transcript variant 6, mRNA.
种属: Human
CDS区长度: 510 (查看编码区序列)
翻译后氨基酸长度: 169 (查看氨基酸序列)
Transcript Variant: This variant (6) differs in its 5' UTR, initiates translation at a downstream start codon, lacks several exons, and its 3'-terminal exon extends past a splice site that is used in variant 1. The encoded isoform (6) is shorter and has a distinct C-terminus, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G124894 人 SENP7 (NM_001282804) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 SENP7 (NM_020654) cDNA克隆 transcript variant 1
人 SENP7 (NM_001077203) cDNA克隆 transcript variant 2
人 SENP7 (NM_001282801) cDNA克隆 transcript variant 3
人 SENP7 (NM_001282802) cDNA克隆 transcript variant 4
人 SENP7 (NM_001282803) cDNA克隆 transcript variant 5
人 SENP7 (NM_001282804) cDNA克隆 transcript variant 6

基因简介

The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for many cellular processes. SUMO-specific proteases, such as SENP7, process SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also display isopeptidase activity for deconjugation of SUMO-conjugated substrates (Lima and Reverter, 2008 [PubMed 18799455]).[supplied by OMIM, Jun 2009]

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