人 ZEB2 (NM_001171653) cDNA克隆

Accession: NM_001171653
基因名称: ZEB2
基因别名: SIP1; SIP-1; ZFHX1B; HSPC082; SMADIP1
基因描述: Homo sapiens zinc finger E-box binding homeobox 2 (ZEB2), transcript variant 2, mRNA.
种属: Human
CDS区长度: 3573 (查看编码区序列)
翻译后氨基酸长度: 1190 (查看氨基酸序列)
Transcript Variant: This variant (2) is missing an in-frame coding exon compared to variant 1, resulting in a shorter isoform (2) lacking an internal protein segment compared to isoform 1.
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G124930 人 ZEB2 (NM_001171653) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jan 2010]